allergy tests
45-1 Ramsey Road, Shirley, NY 11967, USA, Shirley, New York, 11967
About us
Immunoglobin E (IgE) plays a vital role in allergic diseases. The underlying mechanism of IgE-mediated allergy is that: the allergen (second exposure) binds to the pre-existing IgE (produced in the first exposure) cross-linked with the Fc receptors on the surface of mast cells and basophils, resulting in degranulation and the secretion of inflammatory substances such as histamine, leukotriene (LTC4 and LTD4), and prostaglandin.