45-1 Ramsey Road, Shirley, New York 11967, USA, United States, Shirley, New York, 11967
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β-Arrestin GPCR cells are engineered to co-the ProLink (PK) tagged GPCR and the Enzyme Acceptor (EA) tagged β-Arrestin. Activation of the GPCR-PK induces β-Arrestin-EA recruitment, forcing complementation of the two β-galactosidase enzyme fragments (EA and PK). The resulting functional enzyme hydrolyzes substrate to generate a chemiluminescent signal. These cells have been modified to prevent long term propagation and expansion using a proprietary compound that has no apparent effect on assay performance.
https://www.creativebiomart.net/avpr1a-u2os-beta-arrestin-gpcr-assay-kit-462379.htm
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