Base Excision Repair Pathway
(163) 161-9792
45-1 Ramsey Road, Shirley, NY 11967, USA, Shirley, New York, 11967
About us
Base excision repair (BER) corrects small base lesions that do not significantly distort the DNA helix structure. It is initiated by a DNA glycosylase that recognizes and removes the damaged base, leaving an abasic site which is further processed by short-patch repair or long-patch repair. Short-patch repair or long-patch repair largely uses different proteins to complete BER. BER may take place in nuclei or mitochondria, largely using different isoforms of proteins or genetically distant proteins.