BCR signaling pathway

45-1 Ramsey Road, Shirley, NY 11967, USA, https://www.creative-diagnostics.com/bcr-signaling-pathway.htm, Shirley, New York, 11967

About us

B cell antigen receptor (BCR) is a multiprotein complex expressed on the surface of B cells which consists of a ligand binding moiety, the antigen-binding transmembrane immunoglobulin (mIg), paired with the signal transduction moiety, Ig-α/Ig-βheterodimers(CD79a/CD79b). The BCR signaling pathway is crucial for proper B-cell development, activation, proliferation, differentiation and consequently for humoral immune response.

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