Cryo-EM Services
About us
Electron microscopy (EM) has become an extremely popular method for the ultrastructural study of macromolecules, cells and tissues. An aqueous biological sample is frozen rapidly and irradiated with a beam of electrons. A detector senses how the electrons are scattered and a computer reconstructs the 3Dshape of the molecule.
Why you need this service? • You have small amount of materials; • The material is hard to crystallize; • You are looking into the molecules in atomic details; • It is a large biomolecular complex (>150 kDa, up to 2000 Å); • You want to observe the real "native state" structure. See the comparison of Crystallography, NMR, and EM Service Processes: (Take protein as an example)
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