CTLA-4/CD28 Signaling Pathway
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45-1 Ramsey Road, Shirley, NY 11967, USA, Shirley, New York, 11967
About us
CD28 is the best characterized and most effective co-stimulatory molecule expressed by naive and primed T cells. CD28 is a 44-kDa glycoprotein that binds to B7-1 (CD80) and B7-2 (CD86) on antigen-presenting cells (APCs) CD28 might be associate, in its unphosphorylated state, with the serine/threonine protein phosphatase 2A (PP2A).