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Therapeutic peptides and proteins as HIV-1 inhibitors have many advantages, such as high specificity and affinity to their molecular targets, and HIV-1 mutants are difficult to avoid these molecules, and are gradually becoming an alternative strategy for HIV-1 therapy. The concept of targeting peptides to membranes to increase receptor interactions has been long known to peptide chemists. These peptides seem to work through different mechanisms and can prevent viruses from entering in a variety of ways. As an additional advantage, such anti-HIV peptides may have other desired functions, such as antibacterial, anti-parasite, spermicidal, and anticancer activities. With the continuous optimization of peptide stability, production, preparation and release methods, some of these compounds are expected to eventually become new anti-HIV drugs.
https://www.creative-peptides.com/research-areas/hiv-related-peptides.html