MAPKAPK2 (MK2)

MAPKAPK2 (Mitogen-Activated Protein Kinase-Activated Protein Kinase 2) is a Protein Coding gene. Among its related pathways are MAPK targets/ Nuclear events mediated by MAP kinases and NFAT and Cardiac Hypertrophy. This kinase is regulated through direct phosphorylation by p38 MAP kinase. In conjunction with p38 MAP kinase, this kinase is known to be involved in many cellular processes including stress and inflammatory responses, nuclear export, gene expression regulation and cell proliferation. Heat shock protein HSP27 was shown to be one of the substrates of this kinase in vivo.