MHC Tetramer

MHC Tetramers have emerged as an important tool for characterization of the specificity and phenotype of T cell immune response, useful in a large variety of disease and vaccine studies. Peptide-MHC multimers display an antigenic peptide in the MHC binding groove, functioning as a surrogate for recognition events that occur as part of the T cell interaction with antigen-presenting cell. https://www.creativebiolabs.net/mhc-tetramer_62.htm