Nana's Seafood & Soul Uptown

About us

Nana's Seafood & Soul Uptown has become known as a “lead interpreter of Lowcountry cuisine” here in Charleston, South Carolina. We are dedicated to bringing you the freshest cuisine at affordable prices with the friendliest smiles in the city. From red rice, lump crab cakes, and seafood salad, Nana's Seafood & Soul presents an unparalleled menu that gives you the most authentic taste of Charleston. Freshly served seafood 100% of the time, fresh caught, and just right. Contact us at 843-937-9311 to enjoy the best seafood in Charleston.