Non-homologous End-joining Pathway

(163) 161-9792
45-1 Ramsey Road, Shirley, NY 11967, USA, Shirley, New York, 11967

About us

DNA double-strand break (DSB) is one of the most dangerous forms of DNA damage. Unrepaired DSBs will lead cells to undergo apoptosis or senescence. On the other side, mis-processing of DSBs will also result in genomic instability and carcinogenesis. Non-homologous end-joining (NHEJ) is one important pathway in eukaryotic cells responsible for the repair of DSBs.

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