PDE10A1 Assay Kit

45-1 Ramsey Road, Shirley, New York 11967, USA, United States, Shirley, New York, 11967

About us

Phosphodiesterases (PDEs) play an important role in dynamic regulation of cAMP and cGMP signaling. PDE10A is a dual substrate PDE highly expressed in striatal medium spiny neurons. PDE10A inhibitors can improve the cognitive symptoms of schizophrenia, and exhibit potential therapeutic value for Huntington"s disease. PDE10A1 is located in the cytosol, whereas PDE10A2 is a membrane-associated protein.

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