Peptide Design
About us
https://www.creative-peptides.com/services/custom-peptide-design.html
Available Peptides Design Services
De novo Peptide Design
The full de novo peptide design framework is described in detail in the part of de novo peptide design. It consists of three stages: an optimization-based sequence selection, fold specificity calculation, and approximate binding affinity calculation.
Peptide Library Design
Our technical and applications support team can offer advice on library design and experimental set up and analysis. Relating to design, we can advise on the best overlap or offset of peptides to be used in your target application, and then using your full-length protein sequence, we can generate the list of peptides for your library.
Stapled Peptide Design
Stapling is a key technique for stabilizing peptides in an α-helical structure. The resultant stapled peptides are then able to compete efficiently for binding to protein targets involved in protein-protein interactions that are mediated by α-helices.
Cell Penetrating Peptide Design
Cell-Penetrating Peptides (CPPs), also known as protein transduction domains (PTDs) or membrane transduction peptides (MTPs) have been widely used for the intracellular uptake and delivery of various macromolecules, or "cargo", which are associated with the peptides either via covalent bond or through non-covalent interaction, such as TAT family peptides.
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