Recombinant Human GPNMB, His-tagged
(631) 619-7922
45-1 Ramsey Road, Shirley, New York 11967, USA, Shokan, New York, 11967
About us
GPNMB is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. The protein shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential. Two transcript variants encoding different isoforms have been found for this gene.
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