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Ronald P. DeMatteo, MD, FACS

Main: (215) 614-1963
Toll Free: (800) 789-7366
3400 Civic Center Boulevard, Perelman Center for Advanced Medicine, Philadelphia, Pennsylvania, 19104

About us

Dr. DeMatteo is the Chairman of the Department of Surgery and a Surgical Oncologist who specializes in treating diseases of the liver, bile duct, gallbladder, pancreas and abdominal sarcomas (GIST).
His clinical research has focused on liver, bile duct, gallbladder, and pancreas cancers. In addition, he has led several national trials testing the benefit of imatinib mesylate (Gleevec) following surgery for gastrointestinal stromal tumor (GIST), a tumor that usually begins in the stomach or intestine.
In the laboratory he and his colleagues study the immune environment of the liver and tumor immunology, working to develop immune therapies to help prevent tumors from returning after surgery.
Honors

Recognized by America's Top Doctors for 2017 and 2018
Recognized by New York magazine Top Doctors issue: 2014, 2015, 2016
Castle Connolly America's Top Doctors for Cancer (digital guide): 2016, 2017, 2018, 2019, 2020, 2021
Recognized in Philadelphia magazine's annual Top Docs issues: 2018, 2019, 2020 and 2021

2016: Jeroen Pit Science Award, The GIST Life Raft Support Group
2008 - 2010: Society of Surgical Oncology Clinical Investigator Award

Request an appointment with Penn Medicine!

Services abdominal cancer surgery, bile duct cancer surgery, biliary tract cancer surgery, cancer surgery, colon cancer surgery, cryoablation, cytoreduction surgery, gastrointestinal (gi) cancer surgery, gastrointestinal stromal tumor surgery, hepatic artery infusion pump, hepatic artery infusion pump placement, hickman catheter, intestinal cancer surgery, intraarterial chemotherapy of tumors, laparoscopic whipple procedure, liver cancer surgery, liver surgery, minimally invasive gastric tumor surgery, neuroendocrine tumor surgery, pancreas cancer surgery, pancreas head cancer surgery, pancreas tail cancer surgery, pancreatectomy, pancreatic surgery, proximal pancreatectomy, pulmonary radiofrequency ablation, radical subtotal pancreatectomy, retroperitoneal sarcoma resection, small intestine cancer surgery, splenectomy, staging laparotomy, stomach cancer surgery, stomach tumor surgery, surgical management of advanced hepato biliary cancer, surgical management of advanced pancreatic cancer, whipple procedure
Video https://www.youtube.com/watch?v=mF4BdHttZkc

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