scfv sequencing

Creative Biolabs offers customers superior approaches for scFv generation such as the one-stop solution for developing CAR from Hybridoma or Phage Display, which manifest as mature and delicate technologies for scFv construction. Basically, a variable region (Fv) consists of a heavy chain variable region (VH) and a light chain variable region (VL), while a single-chain variable fragment (scFv) normally consists of a VH and a VL connected together via a peptide linker. As the most critical initial step, the generation of specific scFv and optimization of its superior affinity lay down the most basic foundation of an effective and specific CAR-T therapy. Without a doubt, a superior scFv leads to an even more superior CAR-T therapy.