TCR signaling pathway
45-1 Ramsey Road, Shirley, NY 11967, USA, https://www.creative-diagnostics.com/tcr-signaling-pathway.htm, Shirley, New York, 11967
About us
T cells are a subset of lymphocytes that play a crucial role in immune response. T-cell receptor (TCR) is a complex of integral membrane proteins on the surface of T cells, which takes part in the activation of T-cells in response to an antigen. Activation of TCR is triggered by major histocompatibility complex (MHC) molecules on antigen presenting cells (APC) that present antigen peptides to TCR complexes and promote a series of cellular signaling cascades, which eventually result in cellular proliferation, differentiation, cytokine production, and/or activation-induced cell death.