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source: https://www.bocsci.com/wnt-signaling-pathway.html

The Wnt signaling pathway is a highly evolutionarily conserved signaling pathway that is widely present in multicellular organisms. This pathway has an effect on cell proliferation, differentiation, apoptosis, cell polarity, cell migration and invasion, and plays an important role in the development and formation of various organs and pathophysiological processes in adulthood. Numerous studies have shown that changes in the Wnt signaling pathway are closely related to formation and development of tumor, development of degenerative diseases, and changes in stem cell function. More new studies have shown that this pathway is also potentially linked to inflammation, neovascularization, maintenance of immune function, wound healing and tissue regeneration. This pathway is being used as a key hotspot in basic applications and drug development research in each of these areas.